Ciliated Human Respiratory Epithelium: A New Model for Respiratory Syncytial Virus (RSV) Infection. • 774

Respiratory Syncytial Virus (RSV) Infection

Perinatal Lamb Model of Respiratory Syncytial Virus (RSV) Infection

Respiratory syncytial virus (RSV) is the most frequent cause of bronchiolitis in infants and children worldwide. Many animal models are used to study RSV, but most studies investigate disease in adult animals which does not address the unique physiology and immunology that makes infants more susceptible. The perinatal (preterm and term) lamb is a useful model of infant RSV disease as lambs have...

Identification of Respiratory Syncytial Virus (RSV) Genome in the Stool of a Child with Acute Gastroenteritis

Case Report: Some viruses have been reported to cause respiratory and gastroenteric infections simultaneously. In this case we present isolation of human respiratory virus (RSV) type B from diarrheal sample of a 12 months' child with acute gastroenteritis. Results: The results indicated the presence of RSV subtype B genome in all three stool samples. Moreover, no sign of co-infections with oth...

Respiratory syncytial virus and human bronchial epithelium.

BACKGROUND A suitable model for respiratory syncytial virus (RSV) infection has yet to be developed. OBJECTIVE To describe an in vitro model of human respiratory epithelium in primary cell culture linked with a computer microscope interface that allows evaluation and imaging of living RSV-infected respiratory epithelium. DESIGN A descriptive, controlled study. Human bronchial cells were obt...

A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection.

Respiratory syncytial virus (RSV) is the primary cause of lower respiratory tract infection during childhood and causes severe symptoms in some patients, which may cause hospitalization and death. Mechanisms for differential responses to RSV are unknown. Our objective was to develop an in vitro model of RSV infection to evaluate interindividual variation in response to RSV and identify suscepti...